It should be fairly easy. I'm pretty sure that the character animation was done with
Poser, because a couple of those characters look like stock characters for that program made by
Daz-3D (I shop there quite a bit). I think they probably used something else for the rendering, because of the lighting and shadow effects, but I'm not sure what. I've got about half a dozen renderers that I use for Poser art. I'd be willing to bet that they used a post processing program, probably Adobe After Effects, to do some of the special effects and sound compositing.
I've got a few hundred pre-made 3D models of everything from people to dragons, wild animals to cars, and plants to space ships. After I get done working on the UFO animation I'm doing, I'll see if I can't do up something in the way of a full blown 3D animation to show off some options.